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Dabigatran-capsule

Wat is dit medicijn?

DABIGATRAN helpt voorkomen dat bloedplaatjes in uw bloed aan elkaar plakken en een bloedstolsel vormen. Dabigatran wordt gebruikt om bloedstolsels te voorkomen en om het risico op een beroerte te verminderen bij mensen met een bepaald type hartritmestoornis. Dabigatran wordt ook gebruikt voor de behandeling of preventie van bloedstolsels in de aderen van uw benen (diepe veneuze trombose of DVT) of de aders in uw longen (longembolie of PE).

Wat moet mijn zorgverlener weten voordat ik dit geneesmiddel neem?

U mag dabigatran niet gebruiken als u allergisch bent voor, of als u:

Dabigatran kan ertoe leiden dat u gemakkelijker bloedt, vooral als:

Dabigatran kan een zeer ernstig bloedstolsel rond uw ruggenmerg veroorzaken als u een ruggenmergtapje krijgt of spinale anesthesie (epiduraal) krijgt. Dit type bloedstolsel kan langdurige verlamming veroorzaken en kan zich vaker voordoen als:

Om zeker te zijn dat dabigatran voor u veilig is, vertel het uw arts als u:

Het is niet bekend of dit geneesmiddel schadelijk is voor een ongeboren baby. Vertel het uw arts als u zwanger bent of van plan bent zwanger te worden.

Het is niet bekend of dabigatran overgaat in de moedermelk of dat het een zogende baby kan schaden. Vertel het uw arts als u een baby borstvoeding geeft.

Hoe moet ik dit geneesmiddel gebruiken?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take this medicine with a full glass of water. You may take dabigatran with or without food. Do not crush, chew, break, or open a dabigatran capsule. Swallow the pill whole.

Because dabigatran keeps your blood from coagulating (clotting) to prevent unwanted blood clots, this medicine can also make it easier for you to bleed, even from a minor injury such as a fall or a bump on the head. Contact your doctor or seek emergency medical attention if you fall or hit your head, or have any bleeding that will not stop.

If you need surgery, dental work, or any type of medical test or treatment, tell the doctor or dentist ahead of time if you have taken dabigatran within the past 12 hours. You may need to stop taking dabigatran for a short time before you have surgery or other medical procedures.

Do not stop taking dabigatran without your doctor's advice. Stopping the medication can increase your risk of stroke. Your doctor may recommend another medication to prevent blood clots if you need to stop taking dabigatran. Your kidney function may need to be checked with blood tests before and during treatment with dabigatran. Keep the capsules in their original container or blister pack. Do not put dabigatran capsules into a daily pill box or pill organizer.

If you have received more than a 30-day supply of this medication, do not open more than one bottle at a time. Open a new bottle only after all the capsules in the old bottle are gone. Store at room temperature, away from moisture and heat. Keep each capsule in the bottle or blister pack until you are ready to take the medicine. Keep the bottle tightly closed when not in use.

Throw away any unused capsules if it has been longer than 4 months since you first opened the bottle. Capsules stored in a blister pack should be thrown away after the expiration date on the label has passed.

What if I miss a dose?

If you are less than 6 hours late in taking your medicine, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Try not to miss any doses of dabigatran to best prevent a stroke.

What may interact with this medicine?

Before you take dabigatran, tell your doctor if you also take rifampin (Rifater, Rifamate, Rimactane, Rifadin).

Tell your doctor about all your current medicines and any you start or stop using, especially other medicines used to treat or prevent blood clots, such as:

This list is not complete. Other drugs may interact with dabigatran, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What should I watch for while using this medicine?

You should not take dabigatran if you have an artificial heart valve, or if you have any active bleeding from a surgery, injury, or other cause.

Because dabigatran keeps your blood from coagulating (clotting) to prevent unwanted blood clots, this medicine can also make it easier for you to bleed, even from a minor injury such as a fall or a bump on the head. Avoid activities that may increase your risk of bleeding or injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

Dabigatran can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you have a genetic spinal defect, if you have a spinal catheter in place, if you have a history of spinal surgery or repeated spinal taps, or if you are also using other drugs that can affect blood clotting. This type of blood clot can lead to long-term or permanent paralysis.

Get emergency medical help if you have symptoms of a spinal cord blood clot such as back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Do not stop taking dabigatran without your doctor's advice. Stopping the medication can increase your risk of stroke.

What side effects may I notice from this medicine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; pain or tight feeling in your chest, wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur.

Where can I keep my medicine?

Store at room temperature, away from moisture and heat. Keep each capsule in the bottle or blister pack until you are ready to take the medicine. Keep the bottle tightly closed when not in use.

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