Pregabaline capsule

Wat is dit medicijn?

Pregabaline is een anti-epilepticum, ook wel een anticonvulsivum genoemd. Het werkt door impulsen in de hersenen te vertragen die epileptische aanvallen veroorzaken. Lyrica beïnvloedt ook chemische stoffen in de hersenen die pijnsignalen door het zenuwstelsel sturen. Lyrica wordt gebruikt om aanvallen te beheersen en om fibromyalgie te behandelen. Het wordt ook gebruikt voor de behandeling van pijn veroorzaakt door zenuwbeschadiging bij mensen met diabetes (diabetische neuropathie), herpes zoster (postherpetische neuralgie of neuropathische pijn geassocieerd met een dwarslaesie).

Wat moet ik mijn zorgverlener vertellen voordat ik dit geneesmiddel neem?

Ze moeten weten of je een van deze voorwaarden hebt:

• bloeden problemen
• hartziekte, inclusief hartfalen
• geschiedenis van alcohol- of drugsmisbruik
• nierziekte
• zelfmoordgedachten, plannen of poging; een eerdere zelfmoordpoging door u of een familielid
• een ongebruikelijke of allergische reactie op pregabaline, gabapentine, andere medicijnen, voedingsmiddelen, kleurstoffen of conserveermiddelen
• zwanger bent of probeert zwanger te worden of probeert zwanger te worden met je partner
• borstvoeding

Hoe moet ik dit geneesmiddel gebruiken?

Neem dit medicijn via de mond in met een glas water. U kunt dit geneesmiddel met of zonder voedsel innemen. Neem uw doses op gezette tijden in. Neem uw geneesmiddel niet vaker in dan is voorgeschreven. Stop niet met het innemen behalve op advies van uw arts of zorgverlener. Praat met uw kinderarts over het gebruik van dit geneesmiddel bij kinderen. Speciale zorg kan nodig zijn.

Wat moet ik doen in geval van een overdosis?

Als u denkt dat u teveel van dit geneesmiddel heeft ingenomen, neem dan onmiddellijk contact op met een antigifcentrum of een eerstehulpafdeling.

Wat kan interageren met dit geneesmiddel?

• geneesmiddelen voor diabetes, zoals pioglitazon
• geneesmiddelen die worden gebruikt om u te helpen slapen of te ontspannen, zoals lorazepam, alprazolam of diazepam
• recept pijn medicijnen
• rosiglitazon (Avandia, Avandamet, Avandaryl)
• hart- of bloeddrukmedicatie zoals benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace) en anderen.

Deze lijst beschrijft mogelijk niet alle mogelijke interacties. Geef uw zorgverlener een lijst met alle medicijnen, kruiden, medicijnen zonder recept of voedingssupplementen die u gebruikt. Vertel hen ook als u rookt, alcohol drinkt of illegale drugs gebruikt. Sommige items kunnen interageren met uw geneesmiddel.

Wat als ik een dosis mis?

Als u een dosis mist, neem deze dan zo snel mogelijk in. Als het bijna tijd is voor uw volgende dosis, neem dan alleen die dosis. Neem geen dubbele of extra doses in.

Wat moet ik onthouden tijdens het gebruik van dit geneesmiddel?

• Visit your doctor or health care professional for regular checks on your progress.
• Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.
• You may want to keep a personal record at home of how you feel your condition is responding to treatment.
• Share all information regarding your condition with your doctor or health care professional at each visit.
• You should contact your doctor or health care professional if your seizures get worse or if you have any new types of seizures.
• Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, insomnia, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
• Do not stop taking this medicine or any of your seizure medicines unless instructed by your doctor or health care professional.Do not stop using Lyrica without first talking to your doctor, even if you feel fine.
• Stopping your medicine suddenly can increase your seizures or their severity.
• Wear a medical identification bracelet or chain if you are taking this medicine for seizures, and carry a card that lists all your medications.
• If you are taking Lyrica to prevent seizures, keep taking the medication even if you feel fine.
• You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you.
• Call your doctor if you have any problems with your vision while taking Lyrica.
• Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.You may have increased seizures or withdrawal symptoms such as headache, sleep problems, nausea, and diarrhea.
• Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
• If you have a heart condition, like congestive heart failure, and notice that you are retaining water and have swelling in your hands or feet, contact your health care provider immediately.
• The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine.
• Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.
• Ask your doctor how to avoid withdrawal symptoms when you stop using Lyrica.
• Do not change your dose of Lyrica without your doctor's advice.
• Tell your doctor if the medication does not seem to work as well in treating your condition.
• Any medical care provider who treats you should know that you take seizure medication.
• NOTE: This medicine is only for you. Do not share this medicine with others.
• Take Lyrica exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
• FDA pregnancy category C. It is not known whether Lyrica will harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking Lyrica for seizures. Do not start or stop taking Lyrica during pregnancy without your doctor's advice.

What side effects may I notice from this medicine?

Common side effects of Lyrica include:

infection, ataxia, blurred vision, constipation, diplopia, dizziness, drowsiness, fatigue, headache, peripheral edema, tremor, weight gain, visual field loss, accidental injury, and xerostomia.

Other side effects include:

abnormal gait, abnormality in thinking, amnesia, arthralgia, cognitive dysfunction, confusion, edema, neuropathy, sinusitis, speech disturbance, vertigo, visual disturbance, weakness, myasthenia, amblyopia, increased appetite, and twitching. See below for a comprehensive list of adverse effects.

In addition to its needed effects, some unwanted effects may be caused by pregabalin (the active ingredient contained in Lyrica). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking pregabalin:

Less common:

• shortness of breath
• tightness in the chest

Rare

• Blistering, peeling, or loosening of the skin
• chills
• cough
• diarrhea
• difficulty with swallowing
• dizziness
• fast heartbeat
• hives
• itching
• joint or muscle pain
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• red skin lesions, often with a purple center
• red, irritated eyes
• skin rash
• sore throat
• sores, ulcers, or white spots in the mouth or on the lips
• unusual tiredness or weakness

Minor Side Effects

Some of the side effects that can occur with pregabalin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

• Accidental injury
• bloating or swelling of the face, arms, hands, lower legs, or feet
• blurred vision
• burning, tingling, numbness or pain in the hands, arms, feet, or legs
• change in walking and balance
• clumsiness
• confusion
• delusions
• dementia
• difficulty having a bowel movement (stool)
• difficulty with speaking
• double vision
• dry mouth
• fever
• headache
• hoarseness
• increased appetite
• lack of coordination
• loss of memory
• lower back or side pain
• painful or difficult urination
• problems with memory
• rapid weight gain
• sensation of pins and needles
• shakiness and unsteady walk
• sleepiness or unusual drowsiness
• stabbing pain
• swelling
• tingling of the hands or feet
• trembling, or other problems with muscle control or coordination
• unusual weight gain or loss

Less common:

• anxiety
• bloated or full feeling
• burning, crawling, itching, numbness, prickling, tingling feelings
• chest pain
• cold sweats
• coma
• cool, pale skin
• cough producing mucus
• decrease or change in vision
• depression
• excess air or gas in the stomach or intestines
• eye disorder
• false or unusual sense of well-being
• general feeling of discomfort or illness
• increased hunger
• joint pain
• loss of appetite
• loss of bladder control
• loss of strength or energy
• muscle aches and pains
• muscle twitching or jerking
• muscle weakness
• nausea
• nervousness
• nightmares
• noisy breathing
• pain
• passing gas
• rhythmic movement of the muscles
• runny nose
• seizures
• shivering
• slurred speech
• sweating
• trouble sleeping
• twitching
• uncontrolled eye movements
• vomiting

This list may not describe all possible side effects.

Where can I keep my medicine?

Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

lyrica